An Update on Treatment and Outcome of Lupus Nephritis in Children
نویسنده
چکیده
Introduction Lupus nephritis (LN) is one of the main clinical presentations determining the course and outcome of systemic lupus erythematosus (SLE) in children. It occurs in 40–80% of pediatric patients at presentation and can be even higher during the later stages of the disease. The severity of the disease varies from mild glomerulonephritis to severe manifestations leading to end-stage renal disease (ESRD) [1,2]. After the introduction of immunosuppressive therapies in recent decades, the prognosis of SLE has improved, with a 5-year survival of Abstract
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